منابع مشابه
Lead Phytochemicals for Anticancer Drug Development
Cancer is a serious concern at present. A large number of patients die each year due to cancer illnesses in spite of several interventions available. Development of an effective and side effects lacking anticancer therapy is the trending research direction in healthcare pharmacy. Chemical entities present in plants proved to be very potential in this regard. Bioactive phytochemicals are prefere...
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BACKGROUND A novel and accurate high-throughput tandem mass spectroscopic method has been developed and validated for determination of imatinib, a protein-tyrosine kinase inhibitor against chronic myeloid leukemia. MATERIALS & METHODS Chromatographic separation was carried on XTerra® RP18 column (150 mm × 4.6 mm, 5 µm particle size) manufactured by Waters Corporation, MA, USA. The detection w...
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Cancer chemotherapy celebrated its fiftieth anniversary last year. It was in 1945 that wartime research on the nitrogen mustards, which uncovered their potential use in the treatment of leukaemias and other cancers, was first made public. Fifty years later, more than sixty drugs have been registered in the USA for the treatment of cancer, but there are still lessons to be learnt. One problem, p...
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Drug development as a sensitive thermometer represents the scientific and technical power-engines for any countries. As a result, drug manufacture (highly competitive area) is pillar industry for small-range of developed countries and highest medical expenditures worldwide. Nonetheless, new anticancer drug discovery, development and manufacture were entering into bottleneck stage two decades ag...
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The aim of this present article is to underscore the recent evidence linking anticancer activity and free radical scavenging activity of mycotoxins and its significance in the development of newer anticancer drugs. Although acute exposure to a massive amount of mycotoxin is rare but long-term exposure/consumption of food with low levels of lipophilic mycotoxin remains problematic. The aneuploid...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2002
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6600309